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In recent years there has been increasing interest and, subsequently, active research in neuropeptides. These neuroactive molecules coordinate, integrate, and regulate physiological processes in all organisms, throughout all phases of development. Acting as neurohormones, neurotransmitters, and/or neuromodulators, they maintain physiological homeostasis and influence important behavioral patterns. This textbook is the first to bring together and synthesize the neuropeptide research of the past decade in such a comprehensive, scholarly manner.
The book is divided into two parts. In Part I the author defines the basic principles of neuropeptide action, including their biosynthesis, processing, transport, distribution, and interactions with receptors and second messenger systems. Strand also discusses the intimate interaction between the neuropeptides, stress, and the immune system. In Part II she discusses the regulatory functions of the families of neuropeptide in sufficient detail to provide both the advanced student and senior investigator with a thorough understanding of the most important neuropeptides. The text also contains a complete and up-to-date reference/reading list.
- Sales Rank: #2240183 in Books
- Published on: 1999-01-11
- Original language: English
- Number of items: 1
- Dimensions: 8.90" h x 1.70" w x 8.20" l, 3.59 pounds
- Binding: Hardcover
- 658 pages
Review
This book will clearly be considered the bible of the neuroendocrine field.
(Frank Antonawich, Department of Neurology, State University of New York at Stony Brook)This book is a magnificent review of this fascinating subject. Strand presents a wealth of data in a very comprehensive manner. She has summarized the information in a scholarly yet highly comprehensible, lucid way.
(D. de Wied, M.D., Ph.D., Professor Emeritus, Department of Medical Pharmacology, Rudolf Magnus Institute for Neurosciences)Strand has defined the major body of knowledge that makes a basis for a textbook on neuropeptides.
(M. Ian Phillips Regulatory Peptides)This book is a superb compilation of the complexities of the fields of neuropeptides.
(Donlin M. Long, M.D., Ph.D. Neurosurgery Quarterly)...[This] book is a coherent and readable volume that provides a great deal of valuable information.
(Leslie Iverson Trends in Neuroscience) About the Author
Fleur L. Strand is the Carroll and Milton Petrie Professor Emerita of Biology and Neural Science at New York University.
Most helpful customer reviews
0 of 0 people found the following review helpful.
Editorial Reviews- Regulatory Peptides
By A Customer
There is sufficient body of evidence to treat neuropeptides as a field of research worthy of a textbook. Dr. Strand who has masterfully pulled together this evidence, states that "one of the most important functions of neuropeptides is the integration of the functions of the brain and the systems of the body." The list of functions is long and broad but Strand covers them well. This book has the lucid consistency of being written by a single author who is an active researcher in the field of neuropeptides and a teacher of graduate courses on neuropeptides. "Neuropeptides" is an excellent overview and source book for students, teachers and researchers. It is readable and clearly organized throughout. As much as is possible in a field where new findings are constantly being made, Strand has defined the major body of knowledge that makes a basis for a textbook on neuropeptides. The book is organized in two parts: the general characteristics of neuropeptides and the second, neuropeptide families and their regulatory role. Nineteen chapters in all, full of figures, diagrams and tables of summarizing information. Dr. Strand does justice to the literature without overwhelming the reader. She provides a scholarly basis for her chapters with sufficient references backing each chapter, plus a useful list of books and literature reviews relevant to the topic. In summary, "Neuropeptides" is an excellent textbook. The book is perfect for a graduate course or upper-undergraduate level. It is also a great book for anyone working on a particular neuropeptide, to be used whenever they lose sight of the larger field of research that has been established on neuropeptides and want to understand it.
1 of 1 people found the following review helpful.
Editorial Review - Trends in Neurosciences
By A Customer
Given the complexity and rapid growth of research in neuropeptides it is perhaps not surprising that few texts have attempted to give an overview of this field. We should, therefore, be grateful to Fleur Strand for her well-written and comprehensive monograph. The author is an experienced neuroscientist who has been actively involved in research and teaching on the subject of neuropeptides, and the book is a coherent and readable volume that provides a great deal of valuable information to advanced students and others who are interested in neuropeptides. The book is well prepared with clear illustrations, and a comprehensive bibliography and index. The author provides an easily understood review of the many different experimental approaches needed to study the genes, receptors distribution, biosynthesis, release and actions of the neuropeptides. These include molecular neurobiology techniques, immunohistochemical-mapping procedures, the use of genetically engineered animals and studies of peptide actions at the cellular and systemic levels, using neurochemical, neurophysiological and behavioral analyses. A section on the relationship between neuropeptides, stress and the immune system is particularly well prepared, as is the explanation of the physiological roles of neuropeptides in the broader context of biology and evolution. Each chapter concludes with a detailed summary of the conclusions drawn, highlighting the main concepts, which makes for easy review. A concluding section on invertebrate neuropeptides again mixes peptides of neural and non-neural origin but provides a valuable overview of the evolution and biological importance of peptides as chemical signalling molecules.
5 of 5 people found the following review helpful.
THE BEST BOOK I HAVE EVER READ!!!
By A Customer
Neuropeptides is the best book I have ever read! I cannot express how wonderful it is! It was at the top of my x-mas list last year, and since receiving it I have come to value it even more. Strand does a wonderful job of putting together the most up-to-date literature to explain what is known about the neuropeptides. The coverage is extensive also, going from molecular aspects of each neuropeptide to physiological role, and in some cases even to behavior. I feel this is a must have for all graduate students of neuroendocrinology or endocrinology, and this is definately a good reference for researchers in the area.
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